| Date | Status | Player | Injury | Target Return? | Prognosis |
|---|
| 2025-05-15 | Played | Wyatt Langford | Strained oblique | 2025-05-14 | Wyatt Langford played in the game on 2025-05-14 |
| 2025-05-15 | Played | Zach Neto | Shoulder surgery | 2025-05-14 | Zach Neto played in the game on 2025-05-14 |
| 2025-05-15 | Played | Brandon Nimmo | Knee inflammation | 2025-05-14 | Brandon Nimmo played in the game on 2025-05-14 |
| 2025-05-15 | Played | Ramón Urías | Strained hamstring | 2025-05-14 | Ramon Urias played in the game on 2025-05-14 |
| 2025-05-14 | 60-Day IL | Danny Young | Tommy John surgery | 2025-11-01 | Out for 2025 season |
| 2025-05-14 | 60-Day IL | Ben Joyce | Shoulder surgery | 2025-11-01 | Out for 2025 season |
| 2025-05-12 | 10-Day IL | Oswaldo Cabrera | Fractured ankle | 2025-05-25 | No timetable for return |
| 2025-05-12 | 15-Day IL | Ben Lively | Strained forearm flexor | 2025-05-30 | No timetable for return |
| 2025-05-12 | 15-Day IL | Tanner Houck | Strained forearm flexor | 2025-05-30 | No timetable for return |
| 2025-05-12 | 60-Day IL | A.J. Minter | Lat surgery | 2025-11-01 | Out for 2025 season |
| 2025-05-11 | 15-Day IL | T.J. McFarland | Strained groin | 2025-05-30 | No timetable for return |
| 2025-05-11 | 15-Day IL | Bryce Miller | Elbow inflammation | 2025-05-30 | No timetable for return |
| 2025-05-10 | 10-Day IL | Dane Myers | Strained oblique | 2025-05-25 | No timetable for return |
| 2025-05-10 | 10-Day IL | Corey Seager | Strained hamstring | 2025-05-25 | No timetable for return |
| 2025-05-09 | 10-Day IL | Ian Happ | Strained oblique | 2025-05-25 | No timetable for return |
| 2025-05-09 | 15-Day IL | Trent Thornton | Appendicitis | 2025-05-30 | No timetable for return |
| 2025-05-09 | 15-Day IL | Roki Sasaki | Shoulder impingement | 2025-05-30 | No timetable for return |
| 2025-05-09 | 15-Day IL | Jose Quintana | Shoulder impingement | 2025-05-30 | No timetable for return |
| 2025-05-08 | 15-Day IL | Casey Mize | Strained hamstring | 2025-05-30 | No timetable for return |
| 2025-05-07 | 10-Day IL | Andrés Giménez | Strained quad | 2025-05-25 | No timetable for return |
| 2025-05-07 | 10-Day IL | Romy Gonzalez | Quad contusion | 2025-05-25 | No timetable for return |
| 2025-05-07 | 15-Day IL | Hunter Greene | Strained groin | 2025-05-30 | No timetable for return |
| 2025-05-07 | 60-Day IL | Enmanuel Valdez | Shoulder inflammation | 2025-07-14 | No timetable for return |
| 2025-05-06 | 10-Day IL | Jake Fraley | Calf discomfort | 2025-05-25 | No timetable for return |
| 2025-05-06 | 15-Day IL | Hayden Wesneski | Elbow discomfort | 2025-05-30 | No timetable for return |
| 2025-05-06 | 60-Day IL | Tyler Callihan | Forearm surgery | 2025-07-14 | No timetable for return |
| 2025-05-05 | 10-Day IL | Teoscar Hernández | Strained groin | 2025-05-25 | No timetable for return |
| 2025-05-05 | 15-Day IL | Evan Phillips | Forearm discomfort | 2025-05-30 | No timetable for return |
| 2025-05-04 | 10-Day IL | Jesse Winker | Strained oblique | 2025-06-22 | Expected to miss 6-8 weeks |
| 2025-05-04 | 10-Day IL | Andrew Benintendi | Strained calf | 2025-05-25 | No timetable for return |
| 2025-05-04 | 10-Day IL | Triston Casas | Knee surgery (ruptured patellar tendon) | 2025-11-01 | Out for 2025 season |
| 2025-05-04 | 10-Day IL | Noelvi Marte | Strained oblique | 2025-05-25 | No timetable for return |
| 2025-05-04 | 15-Day IL | Shota Imanaga | Strained hamstring | 2025-05-30 | No timetable for return |
| 2025-05-03 | 10-Day IL | Kevin Pillar | Strained lower back | 2025-05-25 | Rehab assignment (5/14) |
| 2025-05-03 | 15-Day IL | Fraser Ellard | Strained lat | 2025-05-30 | No timetable for return |
| 2025-05-02 | 10-Day IL | Otto Lopez | Sprained ankle | 2025-05-25 | No timetable for return |
| 2025-05-02 | 10-Day IL | Yordan Alvarez | Strained hand (right) | 2025-05-25 | Expected to return when eligible or soon thereafte |
| 2025-05-01 | 15-Day IL | Garrett McDaniels | Biceps tendinitis | 2025-05-30 | No timetable for return |
| 2025-05-01 | 15-Day IL | Hunter Bigge | Strained lat | 2025-05-30 | No timetable for return |
| 2025-04-30 | 10-Day IL | Tyler Fitzgerald | Fractured rib | 2025-05-25 | Rehab assignment (5/13) |
| 2025-04-30 | 10-Day IL | Mike Trout | Knee contusion | 2025-05-25 | No timetable for return |
| 2025-04-30 | 15-Day IL | José Ruiz | Neck spasm | 2025-05-30 | Rehab assignment (5/13) |
| 2025-04-29 | 10-Day IL | Tommy Edman | Ankle inflammation | 2025-05-25 | No timetable for return |
| 2025-04-29 | 10-Day IL | Jazz Chisholm Jr. | Strained oblique | 2025-06-03 | Expected to miss 4-6 weeks |
| 2025-04-29 | 60-Day IL | Griffin Conine | Shoulder surgery | 2025-11-01 | Out for 2025 season |
| 2025-04-29 | 60-Day IL | Gregory Santos | Arthroscopic knee surgery | 2025-07-14 | No timetable for return |
| 2025-04-28 | 15-Day IL | Ryan Feltner | Back spasms | 2025-05-30 | No timetable for return |
| 2025-04-28 | 15-Day IL | Paul Sewald | Strained shoulder | 2025-05-30 | No timetable for return |
| 2025-04-27 | 10-Day IL | Luke Raley | Strained oblique | 2025-06-08 | Expected to miss at least 6 weeks |
| 2025-04-27 | 10-Day IL | Jeimer Candelario | Strained back (lumbar spine) | 2025-05-25 | No timetable for return |
| 2025-04-27 | 10-Day IL | Gary Sánchez | Wrist inflammation | 2025-05-25 | No timetable for return |
| 2025-04-27 | 15-Day IL | Tyler Glasnow | Shoulder inflammation | 2025-05-30 | Shut down for 10-14 days |
| 2025-04-26 | 10-Day IL | Jordan Westburg | Strained hamstring | 2025-05-25 | No timetable for return |
| 2025-04-26 | 15-Day IL | Logan Gillaspie | Strained oblique | 2025-05-30 | No timetable for return |
| 2025-04-26 | 15-Day IL | Walker Buehler | Shoulder bursitis | 2025-05-30 | Will likely return on 5/20 |
| 2025-04-26 | 15-Day IL | Forrest Whitley | Sprained knee | 2025-05-30 | Rehab assignment (5/13) |
| 2025-04-25 | 10-Day IL | Luke Keaschall | Fractured forearm | 2025-05-25 | No timetable for return |
| 2025-04-25 | 10-Day IL | Garrett Mitchell | Strained oblique | 2025-05-25 | No timetable for return |
| 2025-04-25 | 10-Day IL | Mason McCoy | Finger dislocation (left pinky) | 2025-05-25 | No timetable for return |
| 2025-04-25 | 10-Day IL | Aaron Schunk | Strained groin | 2025-05-25 | Rehab assignment (5/10) |
| 2025-04-25 | 15-Day IL | Logan Gilbert | Strained elbow flexor | 2025-05-30 | No timetable for return |
| 2025-04-25 | 15-Day IL | Ian Gibaut | Shoulder impingement | 2025-05-30 | Rehab assignment (5/11) |
| 2025-04-24 | 15-Day IL | J.T. Ginn | Elbow inflammation | 2025-05-30 | Rehab assignment (5/14) |
| 2025-04-23 | 10-Day IL | Jake Mangum | Strained groin | 2025-05-25 | No timetable for return |
| 2025-04-23 | 15-Day IL | Kumar Rocker | Shoulder impingement | 2025-05-30 | No timetable for return |
| 2025-04-22 | 60-Day IL | José Leclerc | Strained lat | 2025-07-14 | No timetable for return |
| 2025-04-22 | 60-Day IL | Justin Lawrence | Elbow inflammation | 2025-07-14 | No timetable for return |
| 2025-04-21 | 15-Day IL | Spencer Strider | Strained hamstring | 2025-05-30 | No timetable for return |
| 2025-04-20 | 10-Day IL | Rob Brantly | Strained lat | 2025-05-25 | No timetable for return |
| 2025-04-20 | 15-Day IL | Cody Poteet | Shoulder inflammation | 2025-05-30 | No timetable for return |
| 2025-04-19 | 10-Day IL | Lane Thomas | Bone bruise (wrist) | 2025-05-25 | Rehab assignment (5/13) |
| 2025-04-19 | 15-Day IL | Nick Sandlin | Strained lat | 2025-05-30 | No timetable for return |
| 2025-04-19 | 15-Day IL | Carson Spiers | Shoulder impingement | 2025-05-30 | No timetable for return |
| 2025-04-18 | 10-Day IL | Casey Schmitt | Strained oblique | 2025-05-25 | Rehab assignment (5/13) |
| 2025-04-18 | 60-Day IL | Martín Pérez | Strained elbow flexor | 2025-07-04 | Expected to miss 10-12 weeks |
| 2025-04-18 | 60-Day IL | Tim Mayza | Strained lat | 2025-05-30 | Shut down for at least 6 weeks |
| 2025-04-18 | 60-Day IL | Justin Steele | Elbow surgery (UCL revision repair) | 2025-11-01 | Out for 2025 season |
| 2025-04-17 | 10-Day IL | Richie Palacios | Sprained knee | 2025-05-22 | Expected to miss at least 4-6 weeks |
| 2025-04-17 | 15-Day IL | A.J. Puk | Elbow inflammation | 2025-07-14 | No timetable for return |
| 2025-04-16 | 10-Day IL | Christian Encarnacion-Strand | Lower back inflammation | 2025-05-25 | No timetable for return |
| 2025-04-16 | 15-Day IL | Victor Vodnik | Shoulder inflammation | 2025-05-30 | No timetable for return |
| 2025-04-16 | 60-Day IL | DJ Herz | Tommy John surgery | 2025-11-01 | Out for 2025 season |
| 2025-04-15 | 10-Day IL | Matt Wallner | Strained hamstring | 2025-05-25 | No timetable for return |
| 2025-04-15 | 10-Day IL | Paul DeJong | Fractured nose | 2025-05-25 | No timetable for return |
| 2025-04-15 | 10-Day IL | Austin Slater | Knee surgery (torn meniscus) | 2025-05-25 | Rehab assignment (5/13) |
| 2025-04-15 | 10-Day IL | Ezequiel Tovar | Hip contusion | 2025-05-25 | Rehab assignment (5/10) |
| 2025-04-14 | 10-Day IL | Endy Rodríguez | Finger laceration (right index) | 2025-05-25 | Rehab assignment (5/14) |
| 2025-04-14 | 60-Day IL | Jordan Montgomery | Tommy John surgery | 2025-11-01 | Out for 2025 season |
| 2025-04-14 | 60-Day IL | Jhony Brito | Elbow surgery (internal brace) | 2025-11-01 | Out for 2025 season |
| 2025-04-14 | 60-Day IL | Eli Morgan | Elbow impingement | 2025-07-14 | No timetable for return |
| 2025-04-13 | 60-Day IL | Blake Treinen | Forearm tightness | 2025-07-14 | No timetable for return |
| 2025-04-12 | 10-Day IL | Jose Siri | Fractured shin | 2025-06-14 | Expected to miss 8-10 weeks |
| 2025-04-12 | 10-Day IL | Tyler Freeman | Strained oblique | 2025-05-25 | Rehab assignment (5/10) |
| 2025-04-12 | 15-Day IL | Sam Long | Elbow inflammation | 2025-05-30 | No timetable for return |
| 2025-04-12 | 15-Day IL | Richard Fitts | Strained pectoral | 2025-05-30 | No timetable for return |
| 2025-04-12 | 60-Day IL | Kris Bryant | Lumbar degenerative disc disease | 2025-07-14 | No timetable for return |
| 2025-04-11 | 15-Day IL | Marcus Stroman | Knee inflammation | 2025-05-30 | No timetable for return |
| 2025-04-11 | 60-Day IL | Ryan Bliss | Biceps surgery | 2025-08-24 | Expected to miss at least 4-5 months |
| 2025-04-09 | 10-Day IL | Mike Tauchman | Strained hamstring | 2025-05-25 | Rehab assignment (5/10) |
| 2025-04-09 | 10-Day IL | Korey Lee | Sprained ankle | 2025-05-25 | Rehab assignment (5/9) |
| 2025-04-09 | 15-Day IL | Kevin Kelly | Strained gluteal | 2025-05-30 | No timetable for return |
| 2025-04-08 | 15-Day IL | Orlando Ribalta | Strained biceps | 2025-05-30 | No timetable for return |
| 2025-04-08 | 60-Day IL | Reynaldo López | Arthroscopic shoulder surgery | 2025-07-01 | Shut down for at least 12 weeks |
| 2025-04-07 | 10-Day IL | Jake Rogers | Strained oblique | 2025-05-25 | Rehab assignment (5/13) |
| 2025-04-07 | 15-Day IL | Hunter Harvey | Strained shoulder (teres major) | 2025-05-30 | No timetable for return |
| 2025-04-07 | 15-Day IL | Spencer Arrighetti | Fractured thumb (right) | 2025-05-19 | Expected to miss at least 6 weeks |
| 2025-04-06 | 10-Day IL | Jonny DeLuca | Strained shoulder | 2025-04-27 | Expected to miss at least 2-4 weeks |
| 2025-04-06 | 15-Day IL | Sam Moll | Shoulder impingement | 2025-05-30 | Rehab assignment (4/22) |
| 2025-04-06 | 60-Day IL | Victor Robles | Shoulder dislocation | 2025-06-29 | Expected to miss at least 12 weeks |
| 2025-04-05 | 15-Day IL | Connor Thomas | Elbow arthritis | 2025-05-30 | Rehab assignment (5/21, tentatively) |
| 2025-04-03 | 60-Day IL | Nestor Cortes | Strained elbow flexor | 2025-07-14 | Expected to be out until at least mid-July |
| 2025-04-02 | 15-Day IL | Blake Snell | Shoulder inflammation | 2025-05-30 | No timetable for return |
| 2025-03-30 | 10-Day IL | Dairon Blanco | Achilles tendinopathy | 2025-05-25 | Rehab assignment (4/29) |
| 2025-03-30 | 15-Day IL | Aaron Civale | Strained hamstring | 2025-05-30 | Rehab assignment (5/7) |
| 2025-03-30 | 60-Day IL | Colton Cowser | Fractured thumb (left) | 2025-07-14 | Expected to return in late May or early June |
| 2025-03-29 | 60-Day IL | Jerar Encarnacion | Hand surgery (left) | 2025-07-14 | Rehab assignment (5/10) |
| 2025-03-29 | 60-Day IL | Max Scherzer | Thumb inflammation | 2025-07-14 | No timetable for return |
| 2025-03-28 | 10-Day IL | Josh Lowe | Strained oblique | 2025-05-25 | Rehab assignment (5/6) |
| 2025-03-28 | 60-Day IL | Albert Suárez | Shoulder inflammation | 2025-07-14 | No timetable for return |
| 2025-03-27 | 10-Day IL | Nick Gonzales | Fractured ankle (non-displaced) | 2025-05-25 | No timetable for return |
| 2025-03-24 | 10-Day IL | Zack Gelof | Hamate surgery (right hand) | 2025-05-25 | No timetable for return |
| 2025-03-24 | 15-Day IL | Ryan Brasier | Hip discomfort | 2025-05-30 | Rehab assignment (5/7) |
| 2025-03-23 | 60-Day IL | Wenceel Pérez | Back inflammation | 2025-07-14 | No timetable for return |
| 2025-03-22 | 60-Day IL | Jake Cousins | Strained elbow flexor | 2025-07-14 | No timetable for return |
| 2025-03-22 | 60-Day IL | Shane McClanahan | Triceps nerve-related issue | 2025-07-14 | No timetable for return |
| 2025-03-22 | 60-Day IL | Tyson Miller | Hip impingement | 2025-07-14 | Rehab assignment (4/15) |
| 2025-03-20 | 60-Day IL | Thairo Estrada | Fractured wrist (right) | 2025-05-01 | Out 4-8 weeks |
| 2025-03-18 | 15-Day IL | Declan Cronin | Strained hip | 2025-05-30 | No timetable for return |
| 2025-03-17 | 15-Day IL | Paul Blackburn | Knee inflammation | 2025-05-30 | Rehab assignment (4/19) |
| 2025-03-16 | 60-Day IL | Jared Jones | Elbow discomfort | 2025-07-14 | Resumed throwing on 4/30 |
| 2025-03-14 | 15-Day IL | Derek Law | Forearm inflammation | 2025-05-30 | No timetable for return |
| 2025-03-14 | 60-Day IL | Michael Grove | Shoulder surgery | 2025-11-01 | Out for 2025 season |
| 2025-03-14 | 60-Day IL | Blake Walston | Tommy John surgery | 2025-11-01 | Out for 2025 season |
| 2025-03-14 | 60-Day IL | Nacho Alvarez Jr. | Wrist inflammation | 2025-07-14 | No timetable for return |
| 2025-03-14 | 60-Day IL | Matt Waldron | Strained oblique | 2025-07-14 | No timetable for return |
| 2025-03-14 | 60-Day IL | Prelander Berroa | Tommy John surgery | 2025-11-01 | Out for 2025 season |
| 2025-03-14 | 60-Day IL | Jeff Criswell | Tommy John surgery | 2025-11-01 | Out for 2025 season |
| 2025-03-14 | 60-Day IL | Jon Gray | Fractured wrist (right) | 2025-07-14 | No timetable for return |
| 2025-03-13 | 10-Day IL | Andrés Chaparro | Strained oblique | 2025-05-25 | Rehab assignment (5/14) |
| 2025-03-13 | 15-Day IL | Yu Darvish | Elbow inflammation | 2025-05-30 | Rehab assignment (5/14) |
| 2025-03-12 | 60-Day IL | Cody Bradford | Sprained elbow | 2025-07-14 | No timetable for return |
| 2025-03-12 | 60-Day IL | Alex Faedo | Shoulder inflammation | 2025-07-14 | No timetable for return |
| 2025-03-11 | 60-Day IL | Gerrit Cole | Tommy John surgery | 2025-11-01 | Out for 2025 season |
| 2025-03-07 | 15-Day IL | Andrew Kittredge | Arthroscopic knee surgery | 2025-05-30 | Rehab assignment (5/4) |
| 2025-03-07 | 15-Day IL | Slade Cecconi | Strained oblique | 2025-05-30 | Rehab assignment (4/30) |
| 2025-03-05 | 60-Day IL | Andrew Nardi | Back tightness | 2025-07-14 | No timetable for return |
| 2025-03-05 | 60-Day IL | Grayson Rodriguez | Elbow inflammation | 2025-07-14 | No timetable for return |
| 2025-03-03 | 15-Day IL | Aaron Ashby | Strained oblique | 2025-05-30 | Rehab assignment (5/6) |
| 2025-03-03 | 60-Day IL | Ty Madden | Strained shoulder | 2025-07-14 | No timetable for return |
| 2025-03-02 | 60-Day IL | Austin Gomber | Shoulder soreness | 2025-07-14 | No timetable for return |
| 2025-03-01 | 60-Day IL | Edgardo Henriquez | Foot discomfort | 2025-07-14 | No timetable for return |
| 2025-03-01 | 60-Day IL | Drew Thorpe | Tommy John surgery | 2025-11-01 | Out for 2025 season |
| 2025-02-28 | 15-Day IL | Michael Tonkin | Strained shoulder | 2025-05-30 | Rehab assignment (4/17) |
| 2025-02-28 | 60-Day IL | Luis Gil | Strained lat | 2025-04-11 | Shut down for at least 6 weeks |
| 2025-02-27 | 60-Day IL | Brady Basso | Strained shoulder | 2025-07-14 | No timetable for return |
| 2025-02-26 | 15-Day IL | George Kirby | Shoulder inflammation | 2025-05-30 | Rehab assignment (5/4) |
| 2025-02-25 | 15-Day IL | Scott Effross | Strained hamstring | 2025-05-30 | Rehab assignment (5/6) |
| 2025-02-24 | 60-Day IL | Zack Thompson | Strained lat | 2025-07-14 | No timetable for return |
| 2025-02-23 | 10-Day IL | Matt Vierling | Strained shoulder | 2025-05-25 | Rehab assignment (5/4) |
| 2025-02-23 | 60-Day IL | Nick Madrigal | Fractured shoulder (non-throwing) | 2025-07-14 | Questionable for 2025 season |
| 2025-02-22 | 10-Day IL | Pedro León | Sprained knee | 2025-05-25 | No timetable for return |
| 2025-02-22 | 60-Day IL | Parker Meadows | Upper arm nerve discomfort | 2025-07-14 | No timetable for return |
| 2025-02-22 | 60-Day IL | Sean Manaea | Strained oblique | 2025-07-14 | Shut down thru at least mid-April |
| 2025-02-22 | 60-Day IL | Blake Perkins | Fractured shin | 2025-07-14 | No timetable for return |
| 2025-02-21 | 10-Day IL | Taylor Trammell | Strained calf | 2025-05-25 | No timetable for return |
| 2025-02-21 | 60-Day IL | JT Brubaker | Rib fractures | 2025-07-14 | No timetable for return |
| 2025-02-19 | 60-Day IL | Zach Penrod | Sprained elbow | 2025-07-14 | No timetable for return |
| 2025-02-14 | 15-Day IL | Alex Cobb | Hip inflammation | 2025-05-01 | Out thru at least April |
| 2025-02-14 | 15-Day IL | Clayton Beeter | Shoulder impingement | 2025-05-30 | Rehab assignment (4/20) |
| 2025-02-14 | 15-Day IL | Kutter Crawford | Knee discomfort (patellar tendinopathy) | 2025-05-30 | No timetable for return |
| 2025-02-14 | 15-Day IL | Sam Bachman | Thoracic outlet syndrome | 2025-05-30 | Rehab assignment (5/6) |
| 2025-02-14 | 60-Day IL | Alec Marsh | Shoulder impingement | 2025-07-14 | No timetable for return |
| 2025-02-14 | 60-Day IL | Giancarlo Stanton | Elbow epicondylitis (right and left) | 2025-07-14 | No timetable for return |
| 2025-02-14 | 60-Day IL | Ryan Burr | Shoulder inflammation | 2025-07-14 | Rehab assignment (5/6) |
| 2025-02-14 | 60-Day IL | Erik Swanson | Elbow discomfort (median nerve entrapment) | 2025-07-14 | Rehab assignment (5/9) |
| 2025-02-14 | 60-Day IL | DL Hall | Strained lat | 2025-07-14 | Rehab assignment (5/2) |
| 2025-02-14 | 60-Day IL | Bryan Hoeing | Strained shoulder | 2025-07-14 | Rehab assignment (5/10) |
| 2025-02-14 | 60-Day IL | Anthony Rendon | Hip surgery | 2025-11-01 | Out for 2025 season |
| 2025-02-14 | 60-Day IL | Erik Sabrowski | Elbow inflammation | 2025-07-14 | No timetable for return |
| 2025-02-14 | 60-Day IL | Javier Assad | Strained oblique | 2025-07-14 | No timetable for return |
| 2025-02-12 | 60-Day IL | Tom Murphy | Mid-back disc herniation | 2025-07-14 | No timetable for return |
| 2025-02-12 | 60-Day IL | Frankie Montas | Strained lat | 2025-04-02 | Shut down for 6-8 weeks |
| 2025-02-12 | 60-Day IL | Ky Bush | Tommy John surgery | 2025-11-01 | Out for 2025 season |
| 2025-02-07 | 10-Day IL | Spencer Horwitz | Thumb surgery | 2025-05-25 | Rehab assignment (4/27) |
| 2025-01-14 | 15-Day IL | Rhett Lowder | Strained forearm | 2025-05-30 | Rehab assignment (5/4) |
| 2024-12-16 | 60-Day IL | Braxton Garrett | UCL revision surgery (internal brace) | 2025-11-01 | Out for 2025 season |
| 2024-11-14 | 60-Day IL | Michael Kopech | Forearm inflammation | 2025-07-14 | Rehab assignment (5/8) |
| 2024-11-14 | 60-Day IL | Brusdar Graterol | Shoulder surgery (labrum) | 2025-07-01 | Out thru at least June |
| 2024-11-14 | 60-Day IL | James McArthur | Elbow surgery (fractured olecranon) | 2025-07-14 | No timetable for return |
| 2024-11-13 | 60-Day IL | Josh Sborz | Shoulder surgery (debridement procedure) | 2025-06-01 | Out thru at least May |
| 2024-11-06 | 60-Day IL | Clayton Kershaw | Toe surgery / Knee surgery | 2025-07-14 | Rehab assignment (4/16) |
| 2024-10-30 | 60-Day IL | David Fry | Elbow surgery | 2025-07-14 | No timetable for return |
| 2024-10-29 | 60-Day IL | Joe Jiménez | Knee surgery (cartilage repair) | 2025-08-01 | Out thru at least July |
| 2024-10-11 | 60-Day IL | Joe Musgrove | Tommy John surgery | 2025-11-01 | Out for 2025 season |
| 2024-10-11 | 60-Day IL | Julian Aguiar | Tommy John surgery | 2025-11-01 | Out for 2025 season |
| 2024-10-10 | 60-Day IL | Ha-Seong Kim | Shoulder surgery (torn labrum) | 2025-07-14 | No timetable for return |
| 2024-10-09 | 60-Day IL | Gavin Stone | Shoulder surgery | 2025-11-01 | Out for 2025 season |
| 2024-10-03 | 10-Day IL | Masataka Yoshida | Shoulder surgery (labral repair) | 2025-05-25 | No timetable for return |
| 2024-09-25 | 60-Day IL | Christian Scott | Tommy John surgery (internal brace) | 2025-11-01 | Out for 2025 season |
| 2024-09-18 | 60-Day IL | Sam Hentges | Shoulder surgery | 2025-07-14 | Questionable for 2025 season |
| 2024-09-14 | 60-Day IL | Brandon Williamson | Tommy John surgery | 2025-11-01 | Out for 2025 season |
| 2024-08-25 | 60-Day IL | River Ryan | Tommy John surgery | 2025-11-01 | Out for 2025 season |
| 2024-08-07 | 60-Day IL | Luis Medina | Tommy John surgery | 2025-11-01 | Out for 2025 season |
| 2024-07-30 | 60-Day IL | Kyle Hurt | Tommy John surgery | 2025-07-14 | Questionable for 2025 season |
| 2024-07-24 | 60-Day IL | Josiah Gray | Tommy John surgery (internal brace) | 2025-07-14 | No timetable for return |
| 2024-07-12 | 60-Day IL | Drew Smith | Tommy John surgery (internal brace) | 2025-07-14 | No timetable for return |
| 2024-07-02 | 60-Day IL | J.P. France | Shoulder surgery (capsule tear) | 2025-07-14 | Questionable for 2025 season |
| 2024-06-26 | 60-Day IL | Patrick Sandoval | Elbow surgery (internal brace) | 2025-08-01 | Out thru at least July |
| 2024-06-25 | 60-Day IL | Alex Lange | Lat surgery | 2025-07-14 | No timetable for return |
| 2024-06-24 | 60-Day IL | Robert Gasser | Tommy John surgery | 2025-07-14 | No timetable for return |
| 2024-06-19 | 60-Day IL | Kyle Bradish | Tommy John surgery | 2025-07-14 | Questionable for 2025 season |
| 2024-06-17 | 60-Day IL | Alek Manoah | Elbow surgery (internal brace) | 2025-07-14 | No timetable for return |
| 2024-06-17 | 60-Day IL | Tyler Wells | Elbow surgery (internal brace) | 2025-07-14 | No timetable for return |
| 2024-06-06 | 60-Day IL | Cristian Javier | Tommy John surgery | 2025-07-14 | Questionable for 2025 season |
| 2024-06-05 | 10-Day IL | Ronald Acuña Jr. | Knee surgery (torn ACL) | 2025-05-25 | Rehab assignment (5/13) |
| 2024-06-05 | 60-Day IL | José Urquidy | Tommy John surgery | 2025-07-14 | Questionable for 2025 season |
| 2024-06-03 | 60-Day IL | John Means | Tommy John surgery | 2025-07-14 | No timetable for return |
| 2024-05-29 | 60-Day IL | Brooks Raley | Tommy John surgery (internal brace) | 2025-07-14 | No timetable for return |
| 2024-05-16 | 60-Day IL | Emmet Sheehan | Tommy John surgery | 2025-07-14 | No timetable for return |
| 2024-05-15 | 60-Day IL | Ken Waldichuk | Tommy John surgery/ flexor tendon surgery | 2025-07-14 | No timetable for return |
| 2024-04-30 | 60-Day IL | Robert Stephenson | Tommy John surgery | 2025-07-14 | Rehab assignment (5/13) |
| 2024-04-22 | 60-Day IL | Sawyer Gipson-Long | Elbow surgery (internal brace) | 2025-07-14 | Rehab assignment (5/8) |
| 2024-04-14 | 15-Day IL | Jonathan Loáisiga | Elbow surgery (internal brace) | 2025-05-30 | Rehab assignment (4/26) |
| 2024-04-12 | 60-Day IL | Shane Bieber | Tommy John surgery | 2025-07-14 | No timetable for return |
| 2024-04-10 | 60-Day IL | Chris Murphy | Tommy John surgery | 2025-07-14 | No timetable for return |
| 2024-04-08 | 60-Day IL | Eury Pérez | Tommy John surgery | 2025-07-14 | Rehab assignment (4/26) |
| 2024-03-21 | 60-Day IL | Dauri Moreta | Tommy John surgery | 2025-07-14 | Rehab assignment (4/29) |
| 2024-03-15 | 60-Day IL | Jackson Kowar | Tommy John surgery | 2025-07-14 | Rehab assignment (5/10) |
| 2024-03-14 | 60-Day IL | Trevor Stephan | Elbow surgery (UCL) | 2025-07-14 | No timetable for return |
| 2024-03-01 | 60-Day IL | Mason Thompson | Tommy John surgery | 2025-07-14 | No timetable for return |
| 2024-03-01 | 60-Day IL | Jesse Scholtens | Tommy John surgery | 2025-07-14 | Rehab assignment (5/6) |
| 2024-01-02 | 10-Day IL | Ronny Mauricio | Knee surgery (torn ACL) | 2025-05-25 | Rehab assignment (4/27) |
| 2023-12-06 | 60-Day IL | Johan Oviedo | Tommy John surgery | 2025-07-14 | No timetable for return |
| 2023-10-13 | 15-Day IL | Brandon Woodruff | Shoulder surgery (anterior capsule repair) | 2025-05-30 | No timetable for return |
| 2023-10-11 | 15-Day IL | Kyle Wright | Shoulder surgery (torn capsule) | 2025-05-30 | No timetable for return |
| 2023-05-19 | 60-Day IL | Luis Garcia | Tommy John surgery | 2025-07-14 | No timetable for return |